The France forward scored the only goal as PSG beat Arsenal 1-0 in London in last week’s first leg, but later came off with a hamstring issue.
He played no part in PSG’s 2-1 defeat at Strasbourg in Ligue 1 at the weekend but has since returned to training.
“He is ready but he is not starting the match,” Luis Enrique told broadcaster Canal Plus.
Ghana International Thomas Partey returns to the starting eleven after missing out on the first leg due suspension and now back to the lineup to help his side to a UCL final since 2006 against Barcelona.
Arteta side will be hoping to guide Arsenal to second cupn final since the FA Cup final win against Chelsea under Frank Lampard.
Bradley Barcola therefore joins Desire Doue and Khvicha Kvaratskhelia in PSG’s attack in what is their only change compared to the first leg.
Meanwhile, Thomas Partey returns in midfield for Arsenal after missing last week’s first leg due to suspension.
Mikel Merino therefore reverts to a role through the middle of the attack, with Leandro Trossard on the bench.
Jurrien Timber starts at right-back for the Gunners having been a pre-match fitness doubt.
The winners will advance to the final on May 31 in Munich, where they will play Inter Milan, victors 7-6 on aggregate against Barcelona in an epic last-four tie.
David Raya; Jurrien Timber, William Saliba, Jakub Kiwior, Myles Lewis-Skelly; Martin Odegaard (capt), Thomas Partey, Declan Rice; Bukayo Saka, Mikel Merino, Gabriel Martinelli
It is the first major title for Tottenham since it won the English League Cup in 2008, and its first European triumph since it won its second UEFA Cup — the equivalent of the Europa League now — in 1984.
Brennan Johnson squeezed in the winner at the end of the first half on Wednesday to help Spurs salvage a dismal season, in which it will finish near the bottom of the Premier League standings.
The title guarantees Spurs a spot in next season’s Champions League, and brings some much-needed relief for manager Ange Postecoglou after he struggled to keep his team on track all year.
Tottenham Hotspur’s Brennan Johnson, left, scores their first goal [Vincent West/Reuters]
The victory comes six years after Tottenham fell short against Liverpool in the Champions League final.
The defeat adds pressure on United coach Ruben Amorim, whose team sits in 16th place — just ahead of Tottenham — in the Premier League. The club will not play in any European competition next season.
United came close to equalising the match on Wednesday when a header by Rasmus Hojlund was cleared at the goal line by Tottenham’s Micky van de Ven in the 68th.
Deep into stoppage time, a header by Luke Shaw prompted a difficult save by Tottenham goalkeeper Guglielmo Vicario.
Tottenham Hotspur’s Micky van de Ven clears the ball off the line [Andrew Couldridge/Reuters]
It had been an even match, with neither team creating many significant scoring opportunities, until Tottenham got on the board in the 42nd minute after a cross by Pape Sarr into the area.
The ball ricocheted off Shaw and fell in front of Johnson, who seemed to get just enough of it to poke it across the goal line.
United pressed forward after conceding, but was not able to get the equaliser in front of a split crowd of nearly 50,000 at Athletic Bilbao’s San Mames Stadium.
Manchester United’s captain, Bruno Fernandes, looks dejected as he walks past the trophy after collecting his runners-up medal [Isabel Infantes/Reuters]
United had last won a trophy in the 2024 FA Cup, and its last European triumph was at the 2017 Europa League under manager Jose Mourinho.
The Red Devils lost all four matches against Tottenham this season and is winless against its rival in seven straight games, with the last six under Postecoglou.
United and Tottenham had met in just one previous final — the 2009 League Cup when Alex Ferguson’s United won 4-1 on penalties after a 0-0 draw.
Tottenham striker Son Heung-min, who came off the bench in the 67th, finally ended his decade-long trophy drought with Spurs.